Against Which
| Use attributes for filter ! | |
| Google books | books.google.com |
|---|---|
| Originally published | 2006 |
| Authors | Ross Gay |
| Genres | Poetry |
| Date of Reg. | |
| Date of Upd. | |
| ID | 2920568 |
About Against Which
An exploration of the various ways language can help us transcend both the banal and unusual cruelties which are inevitably delivered to us, and which we equally deliver unto others. These poems comb through violence and love, fear and loss, exploring the common denominators in each. . . .
New Alzheimer's drug slows disease by a third
... Only 1-2% of people have either brain scans or a spinal-fluid analysis to determine whether they actually have Alzheimer s or another form of dementia Against Which the drugs would be useless...
Chris Mason: What's at stake in this week's local elections?
... The benchmark for the vast majority of the elections happening this week That is when they were last fought - and so Against Which comparisons should be made...
Ed Davey: Lib Dem leader to woo Labour voters in conference speech
......
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... But there is definitely a target Against Which we can measure his success or otherwise...
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... But it is a benchmark Against Which Rishi Sunak has asked to be judged...
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... " She went on to insist that as a " servant of democracy" she would defend the legal right to gay marriage " to the hilt" even though she would have voted Against Which codified that right had she been an MSP in 2014...
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... And Against Which Mr Zahawi will be judged...
North Korea: What we can expect from Kim Jong-un in 2023
... He re-started large-scale joint military exercises with the United States, Against Which the North protested and launched more missiles...
New Alzheimer's drug slows disease by a third
By James GallagherHealth and science correspondent
We could be entering the era of Alzheimer's treatments, after The Second drug in under a year has been shown to slow the Disease .
Experts said we were now " on the cusp" of drugs being available, something that had recently seemed " impossible".
The Company Eli Lilly has reported its drug - donanemab - slows the pace of Alzheimer's by about a third.
However two volunteers, and possibly a third, died as a result of dangerous swelling in The Brain .
Sticky gunkDonanemab works in the same way as lecanemab, when it was the proven to slow the Disease .
Both are antibodies like those The Body makes to attack viruses. But these are engineered to clear a sticky gunk from The Brain , called beta amyloid.
Amyloid builds up in the spaces between brain cells, forming distinctive plaques that are one of The Hallmarks of Alzheimer's.
" The decades-long battle to find treatments that change Alzheimer's Disease is changing, " Dr Cath Mummery, the clinical lead for the cognitive-disorders clinic at the UK's National Hospital for Neurology and Neurosurgery, said.
" We Are now entering The Time of Disease modification, where we might realistically hope to treat and maintain someone with Alzheimer's Disease , with long-term Disease management rather than palliative and supportive care. "
The full details of Eli Lilly 's trial have yet to be published - But it has revealed The Key findings:
However, brain swelling was a common side-effect in up to a third of patients.
It was mostly mild or asymptomatic despite being detected on brain scans - But 1. 6% developed dangerous brain swelling, with Two Deaths directly attributed to it and a third volunteer dying after such a case.
" We Are encouraged by the potential clinical benefits that donanemab may provide, although like many effective treatments for debilitating and fatal diseases, there are associated risks that may be serious and life-threatening, " Eli Lilly group vice-president of neuroscience research and development Dr Mark Mintun said.
The Company said it would begin The Process of having its drug approved for use in hospitals in The Next few months.
Dr Liz Coulthard, from the University of Bristol, said there were " significant side-effects" and a lack of long-term data But the drug could " help people live well with Alzheimer's for longer".
'Thought impossible'Having two drugs slow the Disease by targeting amyloid in The Brain has also convinced scientists they are on The Right track after decades of misery and failure.
" This should dispel any lingering doubts about this approach, " Prof John Hardy, from the UK Dementia Research Institute , whose work led to the idea of targeting amyloid, 30 years ago, said. " Having two drugs is great for competition. "
Dr Susan Kolhaas, from Alzheimer's Research UK, said: " We're now on the cusp of a first generation of treatments for Alzheimer's Disease , something that many thought impossible only a decade ago. "
However, these drugs appear to work in only the earliest stages of the Disease - before The Brain is too damaged.
And if they are approved in the UK, it would still take a revolution in how the Disease is diagnosed to make a difference.
Only 1-2% of people have either brain scans or a spinal-fluid analysis to determine whether they actually have Alzheimer's or another form of dementia Against Which the drugs would be useless.
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Related TopicsSource of news: bbc.com