Anaphase-promoting complex photograph

Anaphase-promoting Complex

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About Anaphase-promoting Complex


Anaphase-promoting complex is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome. The APC/C is a large complex of 11–13 subunit proteins, including a cullin and RING subunit much like SCF. Other parts of the APC/C still have unknown functions, but are highly conserved.

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