Bis-tris methane photograph

Bis-tris Methane

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Molar mass209. 2418 g/mol
FormulaC8H19NO5
GHS hazard statementsH315, H319, H335
GHS Signal word Warning
GHS precautionary statementsP261, P305+351+338
Acidity (pKa)6. 46
Date of Reg.
Date of Upd.
ID2170278
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About Bis-tris Methane


Bis-tris methane, also known as BIS-TRIS or BTM, is a buffering agent used in biochemistry. Bis-tris methane is an organic tertiary amine with labile protons having a pKa of 6. 46 at 25 °C. It is an effective buffer between the pH 5. 8 and 7. 2.

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