Colchicine
| Use attributes for filter ! | |
| Formula | C22H25NO6 |
|---|---|
| Molar mass | 399. 437 g/mol |
| CAS ID | 64-86-8 |
| Trade name | Colcrys, Mitigare, others |
| Elimination half-life | 26. 6-31. 2 hours |
| Excretion | Faeces (65%) |
| Metabolism | CYP3A4 |
| Date of Reg. | |
| Date of Upd. | |
| ID | 2951180 |
About Colchicine
Colchicine is a medication used to treat gout and Behçet's disease. In gout, it is less preferred to NSAIDs or steroids. Other uses include the prevention of pericarditis and familial Mediterranean fever. It is taken by mouth. Common side effects include gastrointestinal upset, particularly at high doses.
Extra blood test could help spot heart-attack death risk
An extra Blood Test on suspected heart-attack patients could determine if they are at High Risk of dying in The Next three years, researchers say.
The Test , for the C-reactive protein (CRP), helps detect inflammation and is already used in hospitals to diagnose other conditions.
It could help doctors decide which patients might need more aggressive treatment and closer monitoring.
And this, The National Heart and Lung Institute says, could help save lives.
Doctors currently test for the troponin protein, released into The Blood stream when The Heart is damaged, according to The British Heart Foundation (BHF), which funded the research,
But scientists at The National Heart and Lung Institute and The National Institute for Health Research Health Informatics Collaborative Found CRP tests provided a more detailed picture.
They used data from More Than 250,000 patients admitted to hospital with a suspected Heart Attack .
And researchers now hope to test the anti-inflammatory drug Colchicine - Found to be effective against atherosclerosis, a build-up of fatty deposits in the arteries that increases the chance of a Heart Attack - on patients with high CRP levels.
Cardiologist Dr Ramzi Khamis, who led the research, told Bbc News : " The CRP test is not in the guidelines for a suspected Heart Attack yet - and therefore is not routinely ordered when a patient presents with a suspected Heart Attack .
" It may get proposed for consideration to be included in future [European] Society [of Cardiologists] or NICE [National Institute for Health and Care Excellence] guidelines, which would take all the data into account before issuing a recommendation for its routine use. "
Prof James Leiper, from the BHF, calls The Test a " valuable new tool".
" Every Five Minutes , someone is admitted to a UK hospital with a Heart Attack , " He Said , " and it is estimated that there are 1. 4 million people in the UK who have survived a Heart Attack .
" By better identifying which people are most At Risk , this simple Blood Test could help to direct anti-inflammatory treatments to those who most need it. "
Symptoms of a Heart Attack can include:Source of news: bbc.com