Diphenhydramine photograph

Diphenhydramine

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IUPAC ID2-(diphenylmethoxy)-N,N-dimethylethanamine
FormulaC17H21NO
Elimination half-lifeRange: 2. 4–13. 5 h
Metabolism CYP2D6
CYP3A4
Soluble in Water
ExcretionUrine: 94%; Feces: 6%
Trade nameBenadryl, Unisom, Sominex, others
Date of Reg.
Date of Upd.
ID2173627
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About Diphenhydramine


Diphenhydramine is an antihistamine mainly used to treat allergies. It can also be used for insomnia, symptoms of the common cold, tremor in parkinsonism, and nausea. It is used by mouth, injection into a vein, and injection into a muscle.

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