Dornase alfa (Dornaz Alfa) photograph

Dornase Alfa (Dornaz Alfa)

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ClassificationEnzyme
FormulaC1321H1999N339O396S9
Molar mass29253. 9 g·mol−1
Trade namePulmozyme
ATC codeR05CB13 (WHO)
Music groups Acetylcysteine
Tobramycin
Budesonide
Date of Reg.
Date of Upd.
ID2951553
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About Dornase Alfa (Dornaz Alfa)


Dornase alfa is a highly purified solution of recombinant human deoxyribonuclease I, an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cystic fibrosis patients and reduces viscosity in the lungs, promoting improved clearance of secretions.

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