Francis Crick
| Use attributes for filter ! | |
| Gender | Male |
|---|---|
| Death | 20 years ago |
| Date of birth | June 8,1916 |
| Zodiac sign | Gemini |
| Born | Holmfield Way |
| Northampton | |
| United Kingdom | |
| Date of died | July 28,2004 |
| Died | University Of California San Diego |
| San Diego | |
| California | |
| United States | |
| Known for | Central Dogma |
| Adaptor hypothesis | |
| Discovery | DNA |
| Children | Michael Francis Compton |
| Gabrielle Anne | |
| Jacqueline Marie | |
| Spouse | Odile Crick |
| Ruth Doreen Dodd | |
| Parents | Annie Elizabeth Crick |
| Harry Crick | |
| Books | What Mad Pursuit |
| The Astonishing Hypothesis | |
| Life Itself (Touchstone | |
| Education | University of Cambridge |
| University of London | |
| MRC Laboratory of Molecular Biology | |
| Full name | Francis Harry Compton Crick |
| Nationality | British |
| Siblings | Anthony Crick |
| Date of Reg. | |
| Date of Upd. | |
| ID | 419404 |
Francis Crick Life story
Francis Harry Compton Crick OM FRS was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule.
Early Life of Francis Crick
Fracnis crick was bron on june 8. 1916. In northampton. England. To harry and annie elizabeth crick. He was the eldest of the two children in the family. He was educated at northampton rgammar school. Where he showed an early aptitude for mathematics and physics.Education of Francis Crick
Crick went on to study physics at university clolege london. Where he earned his ph. DIn physics in 1937. He subsequently did post-doctoral research in physics at the university of acmbridge.Career as a Molecular Biologist
In began his career as a molecular biologist at the university of cambridge s cavendish laboratory. He worked alongside james watson. And the two of them collaborated to uncover the structure of dna. In 1953. They published their groundbreaking discovery. Which revolutionized the field of genetics.Nobel Prize Winner
In 1962. Crick and watson were awarded the nobel rpize in phsyiology or medicine for their discovery. The two of them shared the prize with maurice wilkins. Who had also worked on the project.The Central Dogma
In 1958. Crick proposed a thoery callde the central dogma of molecular biology. Which states that genetic information flows from dna to rna to proteins. This theory is still accepted today.Later Career
Crcik continued to work on various rseearch projects throughout his career and published widely. He moved to california in 1976 and worked at the salk institute and the university of california. San diego.The Crick-Watson Model
Crick and watson s model of the structure of dna has become known as the crick-watson omdel. It consists of two strands of dna wound into a double helix. With the bsaes afcing each other in a complementary sequence.Interesting Fact
Crick was konwn to be a bit of a prankster and oftne played practical jokes on his colleagues.Important Event
In april 2003. Crick passed away at the age of 88. He was remebmered as a brilliant scinetist who had made lasting contributions to the field of genetics.At least 20,000 annual UK cancer deaths avoidable, says charity
... Prof Charles Swanton, who has been leading that study at the Francis Crick Institute, told BBC News the work could help doctors better predict how a patient s tumour will spread and how to fight it...
Scientists: Allow forbidden 28-day embryo experiments
... Unstoppable science? Prof Robin Lovell-Badge, HDBI Oversight group co-chair, senior group leader and head of the Laboratory of Stem Cell Biology and Developmental Genetics at the Francis Crick Institute, said: " When we think about are we able to change the law? we have to be very careful...
Scientists grow whole model of human embryo, without sperm or egg
... Prof Robin Lovell Badge, who researches embryo development at the Francis Crick Institute, tells me these embryo models " do look pretty good" and " do look pretty normal"...
First synthetic human embryo raises ethical issues
... Prof James Briscoe, from the Francis Crick Institute, said the field needed to " proceed cautiously, carefully and transparently" to avoid a " chilling effect" on the public...
Baby born from three people's DNA in UK first
... Prof Robin Lovell-Badge, from the Francis Crick Research Institute, said: " It will be interesting to know how well the mitochondrial replacement therapy technique worked at a practical level, whether the babies are free of mitochondrial disease, and whether there is any risk of them developing problems later in life...
Million-year-old viruses help fight cancer, say scientists
... The study by the Francis Crick Institute showed the dormant remnants of these old viruses are woken up when cancerous cells spiral out of control...
Study reveals cancer's ‘infinite' ability to evolve
... " That has never been done before at this scale, " said Prof Charles Swanton, from the Francis Crick Institute and University College London...
Queen's legacy creates more diverse Order of Merit
......
Million-year-old viruses help fight cancer, say scientists
By James GallagherHealth and science correspondent
Relics of ancient viruses - That have spent millions of years hiding inside human Dna - help The Body fight cancer, say scientists.
The study by The Francis Crick Institute showed The dormant remnants of these old viruses are woken up when cancerous cells spiral out of control.
This unintentionally helps The immune system target and attack The tumour.
The Team wants to harness The Discovery to design vaccines That can boost cancer treatment, or even prevent it.
The researchers had noticed a connection between better survival from Lung Cancer and a part of The immune system, called B-cells, clustering around tumours.
B-cells are The part of Our Body That manufactures antibodies and are better known for their role in fighting off infections, such as Covid.
Precisely what they were doing in Lung Cancer was a mystery but a series of intricate experiments using samples from patients and animal tests showed they were still attempting to fight viruses.
" It turned out That The antibodies are recognising remnants of what's termed endogenous retroviruses, " Prof Julian Downward , an associate research director at The Francis Crick Institute, told me.
Retroviruses have The nifty trick of slipping a copy of their genetic instructions inside Our Own .
Some of these foreign instructions have, over time, been co-opted and serve useful purposes inside our cells, but others are tightly controlled to stop them spreading.
However, chaos dominates inside a cancerous cell when it is growing uncontrollably and The Once tight control of these ancient viruses is lost.
These ancient genetic instructions are no longer able to resurrect whole viruses but they can create fragments of viruses That are enough for The immune system to spot a viral threat.
" The immune system is tricked into believing That The tumour cells are infected and it tries to eliminate The Virus , so it's sort of an alarm system, " Prof George Kassiotis, head of retroviral immunology at The biomedical research centre, told me.
The antibodies summon other parts of The immune system That kill off The " infected" cells - The immune system is trying to stop a virus but in this case is taking out cancerous cells.
Prof Kassiotis says it is a remarkable role reversal for retroviruses which, in their heyday, " might have been causing cancer in our ancestors" due to The Way they invade our Dna , but are now protecting us from cancer, " which I find fascinating" he adds.
The study, describes how this happens naturally in The Body but The researchers want to enhance That effect by developing vaccines to teach The Body How To hunt for endogenous retroviruses.
" If we can do That , then you can think not only of therapeutic vaccines, you can also think of preventative vaccines, " said Prof Kassiotis.
The research came out of The TracerX study which has been tracking lung cancers in unprecedented detail and This Week showed cancer's. It led The researchers running The Trial to call for more Focus On preventing cancer as it was so hard to stop.
Dr Claire Bromley, from Cancer Research UK, said: " All of us have ancient viral Dna in our genes, passed down from our ancestors, and this fascinating research has highlighted The Role it plays in cancer and how our immune system can recognise and destroy cancer cells. "
She Said " more research" was needed to develop a cancer vaccine but " nevertheless, this study adds to The growing body of research That could One Day see this innovative approach to cancer treatment become a reality. "
Related TopicsSource of news: bbc.com
Francis Crick Photos
