Leflunomide photograph

Leflunomide

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Molar mass270. 207 g/mol
CAS ID75706-12-6
FormulaC12H9F3N2O2
Trade nameArava, Arabloc, Lunava, others
MetabolismGI mucosa and liver
Elimination half-life14–18 days
Music groups Hydroxychloroquine
Methotrexate
Date of Reg.
Date of Upd.
ID2922128
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About Leflunomide


Leflunomide is an immunosuppressive disease-modifying antirheumatic drug, used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.

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