Methotrexate
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Molar mass | 454. 44 g/mol |
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Formula | C20H22N8O5 |
Metabolism | Hepatic and intracellular |
Elimination half-life | 3–10 hours (lower doses), 8–15 hours (higher doses) |
ATC code | WHO |
Excretion | Urine (80–100%), faeces (small amounts) |
Bioavailability | 60% at lower doses, less at higher doses. |
Date of Reg. | |
Date of Upd. | |
ID | 2951745 |
About Methotrexate
Methotrexate, formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma.