Peter Ratcliffe
| Use attributes for filter ! | |
| Gender | Male |
|---|---|
| Age | 76 |
| Born | Salford |
| United Kingdom | |
| Rank | Major |
| Other name | Billy |
| Battles and wars | Operation Banner |
| Dhofar Rebellion | |
| Falklands War | |
| Gulf War | |
| Awards | Albert Lasker Award for Basic Medical Research |
| Canada Gairdner International Award | |
| Louis-Jeantet Prize for Medicine | |
| Nobel Prize in Physiology or Medicine | |
| Massry Prize | |
| Distinguished Conduct Medal | |
| Date of birth | January 1,1948 |
| Servicebranch | British Army |
| Unit | Special Air Service |
| Parachute Regiment | |
| Year of servic | 1970–1997 |
| Nicknam | Billy |
| Other work | Author |
| Date of Reg. | |
| Date of Upd. | |
| ID | 1663039 |
Peter Ratcliffe Life story
Major Peter Ratcliffe, DCM is a former British Army soldier and commissioned officer who served in the Parachute Regiment and the Special Air Service in a career of almost thirty years, during which he was awarded the Distinguished Conduct Medal for gallantry in action during the Gulf War.
Nobel Prize goes to Neanderthal DNA research
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How our cells sense oxygen wins Nobel prize
... Sir Peter Ratcliffe of the University of Oxford and the Francis Crick Institute, William Kaelin, Harvard, and Gregg Semenza, the Johns Hopkins University the physiology or medicine prize to share...
How our cells sense oxygen wins Nobel prize
Three scientists who have found out how cells sense and adapt to oxygen levels have recovered, the 2019 Nobel Prize .
Sir Peter Ratcliffe of the University of Oxford and the Francis Crick Institute, William Kaelin, Harvard, and Gregg Semenza, the Johns Hopkins University the physiology or medicine prize to share.
their work is leading to new treatments for anemia, and even cancer.
The Role of The oxygen-sensing is also investigated currently, and diseases of Heart Failure , a chronic lung disease.
Sir Peter said: "I am honored and delighted at the news.
"It is a tribute to The Lab , to those who helped me set it up, and worked with me on The Project over The Years , many others in the area, and last but not least My Family for their Forbearance of all the UPS and downs. "
William Kaelin, Sir Peter Ratcliffe and Gregg SemenzaThe Swedish Academy said the award: "The fundamental importance of oxygen has been understood for centuries, but, as the cells have been adapting to changes in the concentrations of oxygen long unknown. "
oxygen levels vary in The Body , in particular:
And if you fall, the cells quickly to their metabolism to adjust.
Why is this important?The oxygen-sensing ability of The Body has an important role in the immune system and the earliest stages of development in the uterus.
to fix If oxygen levels are low, it is the production of Red Blood cells and the construction of the blood vessels can be the cause of this.
More Red Blood cells mean more to transport The Body is able to more oxygen and is the reason why athletes train at altitude.
So, medication, the facial expressions, it is an effective treatment for anemia.
meanwhile, can hijack this process selfish of New Blood vessels and grow.
So, drugs that reverse it can help stop cancer.
"The Work of the three scientists and their teams, has paved the way to a greater understanding of this common, life-threatening conditions, and new strategies to treat it," Dr. Andrew Murray of the University of Cambridge, said.
"congratulations to the three new Nobel laureates. This is highly deserved. "
How was made The Discovery ?the levels of the hormone erythropoietin (EPO) to collect, such as those of oxygen fell.
And The Scientists , was discovered, because a cluster of proteins, the so-called hypoxia-inducible factor (HIF), a modification of the behaviour of DNA, the genetic code.
showed Further work, if oxygen levels were normal, the cells constantly HIF produced only to be destroyed for it, by another protein, VHL.
But if oxygen levels fell, Greek was not. stick to HIF, what change to the build-up to a sufficient extent, the behavior of DNA
Previous winnerscancer, medicine, nobel prize, oxygen, medical research
Source of news: bbc.com
