Sant'Eustachio

Between the Pantheon and Piazza Navona, this neighborhood runs through Rome's historic center to the Largo di Torre Argentina archaeological site. Its central location draws visitors to its high-end hotels and side streets lined with rustic trattorias, while casual bars and cafes attract workday crowds. The Church of San Luigi dei Francesi houses 3 Caravaggio masterworks, including "The Calling of Saint Matthew. "