Tacrolimus photograph

Tacrolimus

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Protein binding≥98. 8%
ExcretionMostly faecal
FormulaC44H69NO12
Other namesFK-506, fujimycin
Trade namePrograf, Advagraf, Protopic, others
Elimination half-life11. 3 h for transplant patients (range 3. 5–40. 6 h)
Metabolism CYP3A4
CYP3A5
Date of Reg.
Date of Upd.
ID2956988
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About Tacrolimus


Tacrolimus, also known as fujimycin or FK506, is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection.

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