Thymidylate synthase photograph

Thymidylate Synthase

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ClassificationEnzyme
Gene ontology0050757
Date of Reg.
Date of Upd.
ID996556
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About Thymidylate Synthase


Thymidylate synthase is an enzyme that catalyzes the conversion of deoxyuridine monophosphate to deoxythymidine monophosphate. Thymidine is one of the nucleotides in DNA. With inhibition of TS, an imbalance of deoxynucleotides and increased levels of dUMP arise. Both cause DNA damage.

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